Cortical maturation assessed by magnetic resonance imaging in unaffected/mildly affected fetuses with cytomegalovirus infection.
Ameth Hawkins-VillarrealA L Moreno-EspinosaK CastilloNadine HahnerOlivier PiconeL MandelbrotI SimonE GratacósA GoncéElisenda EixarchPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2022)
Unaffected and mildly affected CMV-infected fetuses with mild sonographic involvement showed underdeveloped cortical maturation compared to healthy controls. These results suggest that congenital CMV-infection, even in non-severely affected fetuses, which are typically considered of good prognosis, could be related to altered brain cortical structure. Further research is warranted to better elucidate its correlation with neurodevelopmental outcomes. This article is protected by copyright. All rights reserved.