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Shared effects of the clusterin gene on the default mode network among individuals at risk for Alzheimer's disease.

Qing YeFan SuHao ShuLiang GongChun-Ming XieHong ZhouZhi-Jun ZhangFeng Bai
Published in: CNS neuroscience & therapeutics (2017)
The CLU gene could consistently affect the DMN FC with frontal regions among individuals at risk for Alzheimer's disease, and the CLU-T allele was associated with more compensatory neural processes in DMN changes.
Keyphrases
  • functional connectivity
  • cognitive decline
  • copy number
  • genome wide
  • genome wide identification
  • resting state
  • working memory
  • transcription factor