α-Synuclein species in plasma neuron-derived extracellular vesicles as biomarkers for iRBD.
Xuemei WangYuanchu ZhengHuihui CaiWenyi KouChen YangSiming LiBingxu ZhuJiayi WuNing ZhangTao FengXiaohong LiFulong XiaoZhen-Wei YuPublished in: Annals of clinical and translational neurology (2024)
The current study demonstrated that the levels of total α-Syn, α-Syn aggregates, and pS129-containing NDEVs in the plasma of individuals with iRBD were significantly higher compared to HCs. The levels of α-Syn species-containing NDEVs in plasma may serve as biomarkers for iRBD.
Keyphrases