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Hippocampal Atrophy Is Associated with Altered Hippocampus-Posterior Cingulate Cortex Connectivity in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis.

Y C ShihChieh-En Jane TsengFa-Hsuan LinHorng-Huei LiouWen-Yih Isaac Tseng
Published in: AJNR. American journal of neuroradiology (2017)
In left mesial temporal lobe epilepsy with hippocampal sclerosis, the left inferior cingulum bundle undergoes degeneration in tandem with the left hippocampal volume, whereas intrinsic functional connectivity seems to react by compensating the loss of connectivity. Such insight might be helpful in understanding the development of the epileptic network in left mesial temporal lobe epilepsy with hippocampal sclerosis.
Keyphrases
  • temporal lobe epilepsy
  • functional connectivity
  • resting state
  • cognitive impairment
  • blood brain barrier
  • network analysis