Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav 1.7 mutation I234T.

Yang YangTalia AdiPhilip R EffraimLubin ChenSulayman D Dib-HajjStephen G Waxman

Published in: British journal of pharmacology (2017)

This article is part of a themed section on Recent Advances in Targeting Ion Channels to Treat Chronic Pain. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v175.12/issuetoc.

Keyphrases

chronic pain
pain management
spinal cord
cancer therapy
benign prostatic hyperplasia
lower urinary tract symptoms
emergency department
drug delivery
spinal cord injury