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Androsterone glucuronide to dehydroepiandrosterone sulphate ratio is discriminatory for obese Caucasian women with polycystic ovary syndrome.

Li-Wei ChoThozhukat SathyapalanEric S KilpatrickBrian G KeevilAdrian G MillerAnne M CoadyLina AhmedStephen L Atkin
Published in: BMC endocrine disorders (2017)
The ADTG:DHEAS ratio was significantly elevated in obese PCOS compared to non-obese PCOS and controls suggesting that this may be a novel biomarker discriminatory for obese PCOS subjects, perhaps being driven by higher hepatic 5α reductase activity increasing ADTG formation in these women.
Keyphrases
  • polycystic ovary syndrome
  • adipose tissue
  • weight loss
  • insulin resistance
  • metabolic syndrome
  • type diabetes
  • obese patients
  • bariatric surgery
  • pregnancy outcomes