Conjugation of nitrated acetaminophen to Der p1 amplifies peripheral blood monocyte response to Der p1.

Ryan G ThomasBrenda M Rivera ReyesBenjamin M GastonNelki B Rivera AcostaIlya R BedermanLaura A SmithMorgan T SuttonBenlian WangJohn F HuntTracey L Bonfield

Published in: PloS one (2017)

These data suggests 3-nitro-acetaminophen formation and reaction with Der p1 provides a mechanism by which stomach acid or infection-induced low airway pH in patients could enhance the allergic response to proteins such as Der p1.

Keyphrases

peripheral blood
end stage renal disease
ejection fraction
chronic kidney disease
dendritic cells
peritoneal dialysis
machine learning
electronic health record
diabetic rats
patient reported outcomes
big data
polycyclic aromatic hydrocarbons
oxidative stress
data analysis
electron transfer