Evaluation of methanolic crude extract of Linum usitatissimum for the removal of biofilm in diabetic foot isolates.
M HaroonM J IqbalWaseem HassanS AliH AhmedS U HassanPublished in: Brazilian journal of biology = Revista brasleira de biologia (2021)
Linum usitatissimum L is a widely used traditionally for multiple ailments. The present research was carried out to explore the antimicrobial, and anti-biofilm activity of crude extract of Linum usitatissimum L (Lu. Cr). Phytochemical and proximate analyses were performed. The bandages of diabetic foot patients were collected from the various hospitals. The bandages were cultured to isolate the bacterial strains present on it. The disc diffusion method was used to identify the antimicrobial potential whereas the minimum inhibitory concentration of the Lu.Cr were also determined. Proximate analysis confirms moisture content 8.33%, ash content 4.33%, crude protein 21.20%, crude fat 49.2% and crude fiber 5.63%. It was revealed that Gram-positive bacteria are most prevalent among all study groups. Lu.Cr possess significant bactericidal potential against S. aureus among all other microbes. Owing to this potential, linseed coated bandages can be used alternatively for the treatment of diabetic foot.
Keyphrases
- staphylococcus aureus
- pseudomonas aeruginosa
- end stage renal disease
- chronic kidney disease
- oxidative stress
- candida albicans
- newly diagnosed
- ejection fraction
- prognostic factors
- adipose tissue
- healthcare
- biofilm formation
- cystic fibrosis
- human health
- risk assessment
- endothelial cells
- peritoneal dialysis
- small molecule
- gram negative
- multidrug resistant
- protein protein
- binding protein
- patient reported
- municipal solid waste
- patient reported outcomes
- genetic diversity