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Clinical and Histopathological Risk Factors for Radioactive Iodine Refractory Follicular and Oncocytic Thyroid Carcinoma.

Merel T StegengaEvert F S van VelsenLindsey OudijkFrederik A VerburgTessa M van GinhovenRobin P PeetersMarco MediciW. Edward VisserFolkert van Kemenade
Published in: The Journal of clinical endocrinology and metabolism (2024)
To our knowledge, this is the first study that correlates clinical and histopathological risk factors with RAI-refractory disease in FTC and OTC, facilitated by a histopathological revision. In FTC, risk factors for RAI-refractory disease were foremost histopathological characteristics of the primary tumor, whereas in OTC presentation with lymph node and distant metastasis was associated with RAI-refractory disease. Our data can help clinical decision making, particularly in patients at risk for RAI-refractory disease.
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