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Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer.

Chen LiangSi ShiYi QinQingcai MengJie HuaQiangshen HuShunrong JiBo ZhangJin XuXian-Jun Yu
Published in: Gut (2019)
PGK1 is a decisive oncogene in patients with SMAD4-negative PDAC and can be a target for the development of a therapeutic strategy for SMAD4-negative PDAC.
Keyphrases
  • epithelial mesenchymal transition
  • transforming growth factor
  • signaling pathway