Chemo-surgical approach in vulvar leiomyosarcoma: A case report.
Giuseppe CapalboAlessandra LogotetaRoberta GalloIlaria CuccuGabriella GentileFrancesca ArienzoAngela MusellaAngelina PernazzaGiorgia PerniolaViolante Di DonatoLucia ManganaroGiorgio BoganiInnocenza PalaiaPublished in: Tumori (2022)
There are no approved therapeutic protocols for this rare neoplasia. Surgery is the mainstay of treatment. However, it is not always feasible, so neoadjuvant chemotherapy was delivered for downstaging the vulvar lesion. We suppose that neoadjuvant chemotherapy has optimized the possibilities of radical surgery. Despite the anectodical nature of this case presentation, neoadjuvant chemotherapy seems a valid therapeutic option for managing patients with bulky vulvar sarcoma. Further large collaborative studies are warranted to identify the best therapeutic option for these patients.
Keyphrases
- neoadjuvant chemotherapy
- sentinel lymph node
- locally advanced
- lymph node
- minimally invasive
- coronary artery bypass
- end stage renal disease
- rectal cancer
- squamous cell carcinoma
- ejection fraction
- chronic kidney disease
- radiation therapy
- peritoneal dialysis
- surgical site infection
- combination therapy
- high grade
- acute coronary syndrome
- drug delivery
- early stage
- quality improvement
- case report
- replacement therapy
- drug administration