Extract of Pinus densiflora needles suppresses acute inflammation by regulating inflammatory mediators in RAW264.7 macrophages and mice.

Seul-Yong JeongWon Seok ChoiOh Seong KwonJong Seok LeeSu Young SonChoong Hwan LeeSarah LeeJin Yong SongYeon Jin LeeJi Yun Lee

Published in: Pharmaceutical biology (2022)

PINE exerts antioxidant and anti-inflammatory effects by inhibiting the production of inflammatory mediators. Identified flavonoids such as taxifolin and quercetin glucoside can be attributed to effect of PINE.

Keyphrases

oxidative stress
signaling pathway
liver failure
respiratory failure
drug induced
high fat diet induced
aortic dissection
insulin resistance
mechanical ventilation