A Chemoselective N-Arylation Reaction of 2-Aminopyridine Derivatives with Arynes.
Bin ChengJian WeiBing ZuJianfei ZhaoTaimin WangXiaoguang DuanRenqi WangYun LiHongbin ZhaiPublished in: The Journal of organic chemistry (2017)
A chemoselective N-arylation reaction of 2-aminopyridine derivatives with arynes in good to excellent yields has been described. The N-arylation products could be further applied to the facile construction of benzoisoquinuclidines and isoquinuclidines as well as pyrido[1,2-a]benzimidazoles.