Effects of Glutamine Synthetase on Neovascularization in Glioma: In Vivo MR Vessel Size Imaging and Histology.

Tianwei SongDandan WangYanan ZhangHong HaoGuodong LiXiping DingZongtao HuZhi ZhangYan LiuHongzhi WangXianglin LiJunchao Qian

Published in: Current medical imaging (2024)

GS inhibitors significantly reduced angiogenesis in the periphery area of C6 glioma, exerting an inhibitory effect on tumor progression. Thus, GS inhibitors could be potential therapeutic agents for treating glioma. Additionally, in vivo MR vessel size imaging detects changes in vascularrelated parameters after tumor treatment, making it a promising method for detecting neovascularization in glioma.</p>.

Keyphrases

vascular endothelial growth factor
high resolution
diabetic retinopathy
endothelial cells
magnetic resonance imaging
contrast enhanced
computed tomography
mass spectrometry
wound healing