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Inter-study and time-dependent variability of metabolite abundance in cultured red blood cells.

Shivendra G TewariKrithika RajaramRussell P SwiftBobby KwanJaques ReifmanSean T PriggeAnders Wallqvist
Published in: Malaria journal (2021)
The bulk of the data showed high inter-study consistency. The collected data, quantification of an expected abundance variation of RBC metabolites, and characterization of a subset of highly variable metabolites in the RBCs will help in identifying non-specific changes in metabolic abundances that may obscure accurate metabolomic profiling of Plasmodium falciparum and other blood-borne pathogens.
Keyphrases
  • red blood cell
  • plasmodium falciparum
  • electronic health record
  • high resolution
  • endothelial cells
  • mass spectrometry
  • single cell
  • data analysis
  • gram negative
  • wastewater treatment