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Glucocorticoids added to paracetamol and NSAIDs for post-operative pain: A systematic review with meta-analysis and trial sequential analysis.

Emma Ritsmer StormholtJoakim SteinessCecilie Bauer DerbyMia Esta LarsenMathias MaagaardOle Mathiesen
Published in: Acta anaesthesiologica Scandinavica (2023)
Multimodal approaches for post-operative analgesia are favoured, including paracetamol and nonsteroidal anti-inflammatory drugs. In this meta-analysis, pooled results from clinical trials are assessed to describe possible benefit of addition of glucocorticoid treatment for analgesia. The findings did not identify additional benefit, though the certainty of the evidence was not high.
Keyphrases
  • anti inflammatory drugs
  • pain management
  • clinical trial
  • systematic review
  • phase iii
  • chronic pain
  • postoperative pain
  • phase ii
  • ultrasound guided
  • study protocol
  • meta analyses
  • double blind
  • replacement therapy