Increases in Tumor N-Glycan Polylactosamines Associated with Advanced HER2-Positive and Triple-Negative Breast Cancer Tissues.
Danielle A ScottRita CasadonteBarbara CardinaliLaura SpruillAnand S MehtaFranca CarliNicole SimoneMark KriegsmannLucia Del MastroJoerg KriegsmannRichard R DrakePublished in: Proteomics. Clinical applications (2019)
The prevalence of tumor-associated polylactosamine glycans in primary and metastatic breast cancer tissues indicates new mechanistic insights into the development and progression of breast cancers. The presence of these glycans could be targeted for therapeutic strategies and further evaluation as potential prognostic biomarkers.