Pontocerebellar atrophy is the hallmark neuroradiological finding in late-onset Tay-Sachs disease.
Jitka MájovskáAnita HennigIgor NestrasilSusanne A SchneiderHelena JahnováManuela VaněčkováMartin MagnerPetr DušekPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2021)
Given the characteristic clinical course and MRI findings of the pontocerebellar atrophy, late-onset Tay-Sachs disease should be considered in the differential diagnosis of adult-onset cerebellar ataxias.