Bioinformatics identifies predictors of arteriovenous fistula maturation.

Jia LiuDingyao ZhangAnand BrahmandamYutaka MatsubaraMingjie GaoJingru TianBing LiuChang ShuAlan Dardik

Published in: The journal of vascular access (2022)

These data show coordinated, and differential regulation of genes associated with AVF maturation, and different patterns of several pathways are associated with sex differences in AVF failure. Inflammatory and immune responses are activated during AVF maturation and diabetes may impair AVF maturation by altering these responses. These findings suggest several novel molecular targets to improve sex specific AVF maturation.

Keyphrases

immune response
type diabetes
cardiovascular disease
electronic health record
metabolic syndrome
toll like receptor
dendritic cells
skeletal muscle
glycemic control
inflammatory response
single molecule
data analysis
deep learning