Plasma sphingolipids mediate the association between gut microbiome composition and type 2 diabetes risk in the HELIUS cohort: a case-cohort study.

Martin F OverbeekFemke RuttersMax NieuwdorpMark DavidsIrene van ValkengoedHenrike GalenkampBert-Jan van den BornJoline W J Beulens Mirthe Muilwijk

Published in: BMJ open diabetes research & care (2024)

These data suggest that sphingolipids mediate the association between microbiome and T2D risk. Future research is needed to confirm observed findings and elucidate causality on a molecular level.

Keyphrases

type diabetes
emergency department
electronic health record
big data
insulin resistance
current status
single molecule
metabolic syndrome
deep learning
weight loss