An Integrated Dialysis Pharmacometric (IDP) Model to Evaluate the Pharmacokinetics in Patients Undergoing Renal Replacement Therapy.

Astrid BroekerMatthias G VossenFlorian ThalhammerSteven C WallisJeffrey LipmanJason A RobertsSebastian Georg Wicha

Published in: Pharmaceutical research (2020)

The IDP model allows accurate, precise and sensitive characterization of clearanceRRT, adsorption and degradation. Successful quantification of all aspects of clearanceRRT in clinical data demonstrated the benefit of the IDP model as compared to conventional approaches.

Keyphrases

patients undergoing
high resolution
machine learning
deep learning
artificial intelligence
peritoneal dialysis
aqueous solution