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Combination of Allosteric and Orthosteric EGFR Inhibitors for Treating Non-Small-Cell Lung Cancer.

Rachel Mata
Published in: ACS medicinal chemistry letters (2024)
Provided herein are novel combination of allosteric and orthosteric EGFR inhibitors, pharmaceutical compositions, use of such compounds in treating non-small-cell lung cancer, and processes for preparing such compounds.
Keyphrases
  • small cell lung cancer
  • epidermal growth factor receptor
  • small molecule
  • tyrosine kinase