Identification of a Biomarker Panel from Genome-Wide Methylation to Detect Early HPV-Associated Oropharyngeal Cancer.

Brittney L Dickey Ryan M Putney Michael J Schell Anders E Berglund Antonio L Amelio Jimmy J Caudell Christine H Chung Anna R Giuliano

Published in: Cancer prevention research (Philadelphia, Pa.) (2024)

This study identified biomarkers using genome-wide methylation to create a panel capable of discerning early oropharyngeal cancer (OPC) from those without OPC. Such a biomarker panel would be an effective tool to detect OPC early and prevent complications of treatment associated with later diagnosis.

Keyphrases

genome wide
dna methylation
papillary thyroid
squamous cell
copy number
gene expression
risk factors
squamous cell carcinoma
lymph node metastasis
young adults
combination therapy
bioinformatics analysis