Serrated Epithelial Change Is Associated With High Rates of Neoplasia in Ulcerative Colitis Patients: A Case-controlled Study and Systematic Review With Meta-analysis.

Alyssa M ParianBerkeley N LimketkaiReezwana ChowdhuryGala Godoy BrewerGeorge SalemKatie FalloonFlorin SelaruJoanna MeliaMark G Lazarev

Published in: Inflammatory bowel diseases (2022)

Serrated epithelial change is associated with a significantly increased risk of synchronous and metachronous neoplasia including high-grade dysplasia and CRC in patients with UC. Histopathological findings of SEC should warrant closer endoscopic surveillance for CRC.

Keyphrases

high grade
low grade
end stage renal disease
ulcerative colitis
ejection fraction
newly diagnosed
public health
prognostic factors
peritoneal dialysis
patient reported
endoscopic submucosal dissection