Prevention of Post-Transplant Diabetes Mellitus: Towards a Personalized Approach.
Didier DuclouxCécile CourivaudPublished in: Journal of personalized medicine (2022)
Post-transplant diabetes is a frequent complication after transplantation. Moreover, patients suffering from post-transplant diabetes have increased cardiovascular morbidity and reduced survival. Pathogenesis mainly involves beta-cell dysfunction in presence of insulin resistance. Both pre- and post-transplant risk factors are well-described, and some of them may be corrected or prevented. However, the frequency of post-transplant diabetes has not decreased in recent years. We realized a critical appraisal of preventive measures to reduce post-transplant diabetes.
Keyphrases
- type diabetes
- glycemic control
- cardiovascular disease
- insulin resistance
- risk factors
- end stage renal disease
- ejection fraction
- metabolic syndrome
- newly diagnosed
- cell therapy
- chronic kidney disease
- stem cells
- adipose tissue
- high fat diet
- single cell
- skeletal muscle
- weight loss
- polycystic ovary syndrome
- patient reported outcomes
- patient reported