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Gray matter reserve determines glymphatic system function in young-onset Alzheimer's disease: Evidenced by DTI-ALPS and compared with age-matched controls.

Hsin-I ChangChi-Wei HuangShih-Wei HsuShu-Hua HuangKun-Ju LinTsung-Ying HoMi-Chia MaWen-Chiu HsiaoChiung-Chih Chang
Published in: Psychiatry and clinical neurosciences (2023)
Reserved GM mediates the link between the glymphatic system and cognition. Our findings suggest that GM integrity rather than the glymphatic system could serve as a direct cognitive test scores predictor in patients with YOAD.
Keyphrases
  • white matter
  • mild cognitive impairment
  • cognitive decline
  • multiple sclerosis
  • middle aged