Network-based strategies in metabolomics data analysis and interpretation: from molecular networking to biological interpretation.
Leonardo Perez de SouzaSaleh AlseekhYariv BrotmanAlisdair R FerniePublished in: Expert review of proteomics (2020)
Network based analysis is an established method that allows the identification of non-intuitive metabolic relationships as well as the identification of unknown compounds in mass spectrometry. Additionally, the representation of data from metabolomics within the context of metabolic networks is intuitive and allows for the use of statistical analysis that can better summarize relevant metabolic changes from a systematic perspective.