Phylogenetic predictions of carbapenemase activity from the Guiana extended-spectrum (GES) family of β-lactamases.

Published in: JAC-antimicrobial resistance (2024)

Data indicate that the substitutions G170S and G243A are associated with carbapenemase activity. The substitutions Q43E, E104K and T237A are most likely associated with ESBL activity.

Keyphrases

klebsiella pneumoniae
escherichia coli
acinetobacter baumannii
gram negative
machine learning
big data
pseudomonas aeruginosa
cystic fibrosis