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Second-line chemotherapy after early disease progression during first-line chemotherapy containing bevacizumab for patients with metastatic colorectal cancer.

Shun YamamotoKengo NagashimaTakeshi KawakamiSeiichiro MitaniMasato KomodaYasushi TsujiNaoki IzawaKentaro KawakamiYoshiyuki YamamotoAkitaka MakiyamaKentaro YamazakiToshiki MasuishiTaito EsakiTakako Eguchi NakajimaHiroyuki OkudaToshikazu MoriwakiNarikazu Boku
Published in: BMC cancer (2021)
In mCRC patients who experienced early progression in first-line chemotherapy, second-line chemotherapy showed poor clinical outcomes regardless use of anti-angiogenic agents.
Keyphrases
  • metastatic colorectal cancer
  • locally advanced
  • squamous cell carcinoma
  • chemotherapy induced