What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review.
Helena BlakewayV Van-de-VeldeV B AllenGeorgios KravvasL PallaM J PageCarsten FlohrRichard B WellerAlan D IrvineT McPhersonA RobertsH C WilliamsN ReynoldsSara J BrownLavinia PaternosterSinéad M Langannull nullPublished in: The British journal of dermatology (2020)
Evidence on FLG-environment interactions in AD aetiology is limited. However, many of the studies lacked large enough sample sizes to assess these interactions fully. Further research is needed with larger sample sizes and clearly defined exposure assessment. Linked Comment: Park and Seo. Br J Dermatol 2020; 183:411.