COVID-19 severity gradient differentially dysregulates clinically relevant drug processing genes in nasopharyngeal swab samples.

Chukwunonso K NwabufoJessica LucAllison McGeerJeremy Alexander HirotaSamira MubarekaAndrew C DoxeyTheo J Moraes

Published in: British journal of clinical pharmacology (2024)

The severity of COVID-19 is associated with the dysregulation of DMETs involved in processing commonly prescribed drugs, suggesting potential disease-drug interactions, especially for narrow therapeutic index drugs.

Keyphrases

coronavirus disease
sars cov
drug induced
respiratory syndrome coronavirus
genome wide
emergency department
bioinformatics analysis
human health
genome wide analysis