Biocompatibility of Biomaterials for Tissue Regeneration or Replacement.

Emerging biomaterials for tissue engineering applications witness a multitude of interaction (both along their interface and internally) with human tissue. Insufficient consideration of the spatial and temporal aspects of these biomaterial-tissue interactions often raise biocompatibility concerns. This review focuses on strategies implemented in some of the recently developed biomaterials-particularly for soft and hard tissue regeneration or replacement-to overcome potential foreign body response and ensure effective functioning of the biomaterial.