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Bilateral Leydig Cell Hyperplasia: A Rare Cause of Postmenopausal Hirsutism.

S PathmanathanNeomal De SilvaM SumanatillekeDilani LokuhettyU V V Ranathunga
Published in: Case reports in endocrinology (2022)
Evaluation of postmenopausal hirsutism needs careful history and examination followed by biochemical evaluation and imaging. While adrenal and ovarian venous sampling can help to arrive at a diagnosis, it is a technically demanding procedure with low success rates even at centers of excellence. Therefore, in such situations, bilateral oophorectomy may be the best course of action which will give the histological confirmation of the diagnosis. Successful treatment of hyperandrogenism can result in improvement of glycaemic control. Bilateral diffuse Leydig cell hyperplasia is a rare but important cause of postmenopausal hirsutism.
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