Effect of SHR0302 on the Pharmacokinetics of CYP3A4, CYP2C8, CYP2C9, and CYP2C19 Probe Substrates in Healthy Volunteers: A Cocktail Analysis.

Meng FuLin LuoSheng FengHongda LinZekun LuFei GuYang FanBing WuJianying HuangKai Shen

Published in: British journal of clinical pharmacology (2023)

The results demonstrated that co-administration of SHR0302 8mg once daily is unlikely to have a clinically meaningful effect on the exposure of drugs metabolized by CYP3A4, CYP2C8, CYP2C9, and CYP2C19 in healthy subjects.

Keyphrases

living cells
fluorescent probe