Long-term SARS-CoV-2-specific and cross-reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology.
Ida LaurénSebastian HavervallHenry NgMartin LordAleksandra PettkeNina Greilert-NorinLena GabrielssonAikaterini ChourliaCatarina Amoêdo-LeiteVijay S JosyulaMohamed EltahirIliana KerzeliAugust Jernbom FalkJonathan HoberWanda ChristAnna WibergMy HedhammarHanna TegelJoachim BurmanFeifei XuElisa PinAnna MånbergJonas KlingströmGustaf ChristofferssonSophia HoberPeter NilssonMia PhilipsonPierre DönnesRobin LindsayCharlotte ThålinSara M MangsboPublished in: Immunity, inflammation and disease (2022)
Using a large cohort and a SARS-CoV-2-specific peptide pool we were able to substantiate that initial disease severity and symptoms correlate with the magnitude of the SARS-CoV-2-specific memory T cell responses.