Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) Antibody Responses in Children With Multisystem Inflammatory Syndrome in Children (MIS-C) and Mild and Severe Coronavirus Disease 2019 (COVID-19).
Elizabeth M AndersonCaroline DiorioEileen C GoodwinKevin O McNerneyMadison E WeirickSigrid GoumaMarcus J BoltonClaudia P ArevaloJulie ChasePhilip HicksTomaz B ManzoniAmy E BaxterKurt P AndreaChakkapong BurudpakdeeJessica H LeeLaura A VellaSarah E HenricksonRebecca M HarrisE John WherryPaul BatesHamid BassiriEdward M BehrensDavid T TeacheyScott E HensleyPublished in: Journal of the Pediatric Infectious Diseases Society (2021)
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) antibody responses in children remain poorly characterized. Here, we show that pediatric patients with multisystem inflammatory syndrome in children (MIS-C) possess higher SARS-CoV-2 spike immunoglobulin G (IgG) titers compared with those with severe coronavirus disease 2019, likely reflecting a longer time since the onset of infection in MIS-C patients.