Parallel Analyses of Somatic Mutations in Plasma Circulating Tumor DNA (ctDNA) and Matched Tumor Tissues in Early-Stage Breast Cancer.

Xianyu ZhangWeiwei ZhaoWei WeiZilong YouXiaohua OuMingming SunYanling YinXiaoyan TangZhen ZhaoChangming HuFeifei LiuJunhao DengLinlin MaoDanyan ZhouYuxia RenXiaoxia LiShangfei ZhangJingshu GengGuodong YaoBingbing SongDalin LiYongdong JiangYanbo ChenYashuang ZhaoShihui YuDa Pang

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

These data showed that ctDNA evaluation is a feasible, sensitive, and specific biomarker for diagnosis and differential diagnosis of patients with early-stage breast cancer who need chemotherapy.

Keyphrases

circulating tumor
early stage
cell free
circulating tumor cells
sentinel lymph node
gene expression
electronic health record
big data
locally advanced
radiation therapy
copy number
machine learning
young adults
rectal cancer