Early-onset type 2 diabetes is associated with genetic variants of β-cell function in the Chinese Han population.

Xiaomu KongXiaoyan XingXuelian ZhangJing HongWenying Yang

Published in: Diabetes/metabolism research and reviews (2019)

Our findings indicate a strong genetic predisposition for EOD, which can be mainly attributed to genetic variants linked to β-cell function, suggesting the β-cell dysfunction plays a key role in the pathogenesis of EOD in Chinese Han individuals.

Keyphrases

early onset
type diabetes
late onset
single cell
cell therapy
oxidative stress
genome wide
glycemic control
stem cells
adipose tissue