δ-Tocotrienol is the Most Potent Vitamin E Form in Inhibiting Prostate Cancer Cell Growth and Inhibits Prostate Carcinogenesis in Ptenp-/- Mice.

Hong WangWilliam YanYuhai SunChung S Yang

Published in: Cancer prevention research (Philadelphia, Pa.) (2022)

We demonstrated that δ-tocotrienol is the most active vitamin E form in inhibiting the growth of several prostate cancer cell lines. In transgenic Ptenp-/- mice, δ-tocotrienol inhibited the formation of prostate cancer. This result would encourage and help design clinical studies for the application of δ-tocotrienol for prostate cancer prevention.

Keyphrases

prostate cancer
radical prostatectomy
signaling pathway
high fat diet induced
adipose tissue
metabolic syndrome
benign prostatic hyperplasia