Effect of Bronchodilation, Exercise Training, and Behavior Modification on Symptoms and Physical Activity in Chronic Obstructive Pulmonary Disease.
Thierry TroostersFrançois MaltaisNancy LeidyKim L LavoieMaria SedenoWim JanssensJudith M Garcia-AymerichDamijan ErzenDorothy De SousaLawrence KorduckiAlan HamiltonJean BourbeauPublished in: American journal of respiratory and critical care medicine (2019)
Tiotropium/olodaterol, with or without ExT, improved EET in patients with COPD taking part in an SMBM program. Combination bronchodilation, with or without ExT, did not provide additional increases in objective PA compared with SMBM alone but did reduce PA-related dyspnea and difficulty. Clinical trial registered with www.clinicaltrials.gov (NCT02085161).