Contemporary trends and outcomes of thrombolytic therapy for acute lower extremity ischemia.
Jonathan BathRyan J KimViktor Y DombrovskiyTodd R VogelPublished in: Vascular (2018)
Thrombolysis remains an effective treatment for acute limb ischemia with increased utilization over time. There was a significant increase in thrombolysis and endovascular procedure leading to improved outcomes. Thrombolysis alone carried the highest mortality and stroke rate, with T+OPEN associated with the highest amputation and complications. Although thrombolysis is effective, 25% of patients required an open procedure suggesting that patient selection for thrombolysis first instead of open surgery continues to be a clinical challenge.
Keyphrases
- pulmonary embolism
- acute ischemic stroke
- minimally invasive
- liver failure
- end stage renal disease
- respiratory failure
- aortic dissection
- chronic kidney disease
- newly diagnosed
- risk factors
- atrial fibrillation
- peritoneal dialysis
- type diabetes
- drug induced
- cardiovascular events
- prognostic factors
- cardiovascular disease
- coronary artery bypass
- insulin resistance
- extracorporeal membrane oxygenation
- subarachnoid hemorrhage
- percutaneous coronary intervention