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CD304/neuropilin-1 is a very useful and dependable marker for the measurable residual disease assessment of B-cell precursor acute lymphoblastic leukemia.

Pratyusha GudapatiTwinkle KhankaGaurav ChatterjeeSitaram GhogaleYajamanam BadrinathNilesh DeshpandeJagruti PatilGaurav NarulaDhanalaxmi ShettyShripad BanavaliNikhil V PatkarSumeet GujralPapagudi G SubramanianPrashant Ramesh Tembhare
Published in: Cytometry. Part B, Clinical cytometry (2020)
CD304 is commonly expressed in leukemic blasts of BCP-ALL. It is very useful in distinguishing residual disease from hematogones and is a fairly dependable marker. Hence, it is a valuable addition for enhancing the sensitivity and applicability of MFC-based MRD assay in BCP-ALL.
Keyphrases
  • acute lymphoblastic leukemia
  • acute myeloid leukemia
  • nk cells
  • allogeneic hematopoietic stem cell transplantation
  • high throughput