Risk of Urogenital Bacterial Infection with Sodium-Glucose Cotransporter-2 Inhibitors: A Retrospective Cohort Study Using a Claims Database.
Takanori ImaiNaoto KatoNaoki KandaHideki HashimotoHayato YamanaShuji HatakeyamaPublished in: Diabetes therapy : research, treatment and education of diabetes and related disorders (2024)
SGLT2 inhibitors were associated with a reduced risk of UTI and an increased risk of genital bacterial infection. They showed no significant association with perineal soft tissue infection when compared to DPP-4 inhibitors. Future research should explore broader demographics, focusing on the elderly and achieving gender balance, to gain a comprehensive understanding of infection risks.