The Apparent Diffusion Coefficient (ADC) is a useful biomarker in predicting metastatic colon cancer using the ADC-value of the primary tumor.
Elias NeradAndrea Delli PizziDoenja M J LambregtsMonique MaasSharan WadhwaniFrans C H BakersHarrie C M van den BoschRegina G H Beets-TanMax J LahayePublished in: PloS one (2019)
The ADC-value of the primary tumor has the potential to predict advanced colon cancer, defined as lymph node metastasis or distant metastasis, with lower ADC values significantly associated with advanced tumors. Furthermore the ADC-value of the primary tumor increases the prediction accuracy of lymph node metastasis compared with morphological criteria.