Decoding the Mechanism of CheReCunJin Formula in Treating Sjögren's Syndrome Based on Network Pharmacology and Molecular Docking.

Xiaoyu Xu Linshuang WangQian ChenZikang WangXun PanXike PengMiao WangDongfeng Wei Yanping Li Bin Wu

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

The results showed that CRCJ could activate multiple pathways and treat SS through multiple compounds and targets. This study lays a foundation for better elucidation of the molecular mechanism of CRCJ in the treatment of SS, and also provides basic guidance for future research on Chinese herbal compounds.

Keyphrases

molecular docking
molecular dynamics simulations
case report
combination therapy
disease activity
human milk
systemic lupus erythematosus
preterm infants
replacement therapy
network analysis