Sequence variants in the proximal promoter and +5.8-kb site of ABO in Koreans with weak B phenotypes.

HongBi Yu Tae Yeul KimSue Jin MoonYoo Na ChungHwa Jong YooJeong Hoon KimDuck Cho

Published in: Vox sanguinis (2021)

Our study demonstrates that sequence variants in the proximal promoter and +5.8-kb site account for a substantial proportion of weak B subgroups in Koreans, suggesting that molecular analysis of these regions is essential for the accurate determination of ABO genotypes in Koreans with weak B phenotypes.

Keyphrases

dna methylation
copy number
transcription factor
gene expression
high resolution
genome wide
amino acid
solid phase extraction
single molecule
mass spectrometry