Intergenerational influence of paternal physical activity on the offspring's brain: A systematic review and meta-analysis.

Parvin Goli Maryam YazdiParnian PoursafaRoya Kelishadi

Published in: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience (2020)

These results suggest an intergenerational effect of paternal physical activity on cognitive benefit, which may be associated with hippocampal epigenetic programming in offspring. However, the biological mechanisms of this modulation remain to be determined.

Keyphrases

physical activity
high fat diet
body mass index
cerebral ischemia
dna methylation
gene expression
white matter
resting state
metabolic syndrome
multiple sclerosis
functional connectivity
blood brain barrier