Insulin resistance contributes more to the increased risk for diabetes development in subjects with low lipoprotein(a) level than insulin secretion.

Eun-Jung RheeJung Hwan ChoDa Young LeeHyemi KwonSe Eun ParkCheol-Young ParkKi-Won OhSung-Woo ParkWon Young Lee

Published in: PloS one (2017)

The subjects with low baseline Lp(a) level showed higher risk for development of diabetes compared with high baseline Lp(a) level, and this was prominent in those with IR than in those with impaired IS.

Keyphrases

type diabetes
insulin resistance
cardiovascular disease
glycemic control
metabolic syndrome
skeletal muscle
polycystic ovary syndrome
weight loss
high fat diet induced