Thrombomodulin facilitates peripheral nerve regeneration through regulating M1/M2 switching.
Tzu-Chieh HuangHua-Lin WuSzu-Han ChenYun-Ting WangChia-Ching WuPublished in: Journal of neuroinflammation (2020)
Collectively, our findings demonstrate the anti-inflammatory role of TM during nerve regeneration. Therefore, TM represents a potential drug for the promotion and modulation of functional recovery in peripheral nerves that acts by regulating the M1/M2 ratio.