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Differences between familial and sporadic dilated cardiomyopathy: ESC EORP Cardiomyopathy & Myocarditis registry.

Folkert W. AsselbergsArjan SammaniPerry Mark ElliottJuan Ramon Gimeno-BlanesLuigi TavazziMichael TenderaJuan Pablo Pablo KaskiAldo Pietro MaggioniPawel P RubisRuxandra JurcutTiina HeliöLeonardo CalòGianfranco SinagraMarija ZdravkovicIacopo OlivottoAušra KavoliūnienėCécile LarocheAlida L P CaforioPhilippe Charronnull null
Published in: ESC heart failure (2020)
We observed that FDCM and SDCM have significant differences at baseline but similar short-term prognosis. Whether modification of associated cardiovascular risk factors provide opportunities for treatment remains to be investigated. Our results also show a prevalent role of genetics in FDCM and a non-marginal yield in SDCM although genetic testing is largely neglected in SDCM. Limited genetic testing and heterogeneity in panels provides a scaffold for improvement of guideline adherence.
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